The Restorative Power of Deep Sleep

How It Impacts Cognition in Lyme Disease Patients

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Jemsek Specialty Clinic

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Within the realm of health and wellness, the importance of a restful night’s sleep cannot be emphasized enough. Its value becomes even more evident when considering its profound influence on the cognitive functions of individuals diagnosed with Lyme disease.

Sleep is an indispensable element of our existence, playing a pivotal role in maintaining our overall physical and mental health. Yet, for those individuals grappling with Lyme disease, achieving a peaceful night’s sleep can be a daunting journey. In addition to coping with the multifaceted symptoms linked to Lyme disease, they frequently confront irregular sleep cycles. In this piece, we will embark on an exploration of the cryptic realm of sleep disruptions associated with Lyme disease, while shedding light on the vital importance of deep sleep in the restoration of cognitive functions for Lyme patients and provide insights into effective strategies for addressing sleep challenges in Lyme disease.

Phases of sleep

NREM sleep is composed of three stages, each progressively deeper and more challenging to rouse a person from. Stage 1 represents the initial phase of light sleep, Stage 2 exhibits a more tranquil state with intermittent bursts of brain activity, and Stage 3 characterizes deep sleep marked by delta wave brain patterns. Deep sleep plays a crucial role in facilitating physical recovery, bolstering the immune system, and supporting cognitive functions. These deep sleep stages tend to be longest during the first half of the night and gradually shorten as the night unfolds, making way for an increased occurrence of REM sleep in later periods.

REM, or Rapid Eye Movement, sleep is characterized by heightened brain activity, temporary muscle paralysis, and the emergence of vivid dreams. This phase is believed to be fundamental for cognitive processes such as memory consolidation, learning, and creativity, often featuring the most vivid dreams during the course of the night’s sleep. Ordinarily, REM sleep commences around 90 minutes into the sleep cycle and tends to extend as the night progresses, particularly in the latter part of the night. While the initial REM stage may be brief, subsequent stages can span up to an hour, constituting approximately 25% of an adult’s total sleep duration.


What happens when deep sleep is disrupted, and how does it affect Lyme disease patients, who are already grappling with the challenges posed by this complex and often debilitating illness?

Lyme Disease: A Complex Culprit

Lyme disease stems from the Borrelia burgdorferi bacterium and is predominantly transmitted through tick bites. While it is well-known for its physical symptoms, including fatigue, joint pain, fever, and skin rashes, Lyme disease also significantly disrupts sleep patterns. Numerous individuals grappling with Lyme disease often struggle with falling asleep, staying asleep, and attaining the rejuvenating deep sleep necessary for overall well-being. The causes of these sleep disruptions are intricate and manifold. The illness itself can induce pain, discomfort, and inflammation, all of which can serve as obstacles to a restful night’s sleep. Furthermore, Lyme disease frequently co-occurs with other tick-borne infections, such as Babesia or Bartonella, which can exacerbate the disturbances in sleep patterns. Lyme disease and its co-infections can intensify Herxheimer reactions, which are also recognized for triggering anxiety and contributing to sleep disturbances, further compounding anxiety.

The Vicious Cycle of Poor Sleep and Cognitive Decline

Here’s where the challenge becomes more complex: inadequate sleep can set in motion a detrimental cycle of cognitive decline for individuals affected by Lyme disease.

  1. Sleep Deprivation: Diminished sleep quality often leads to sleep deprivation.
  2. Memory Impairment: Sleep deprivation hinders memory consolidation, making it challenging for Lyme patients to retain crucial information, including their treatment plans and medical history.
  3. Emotional Instability: Inadequate deep sleep can contribute to emotional instability and increased stress, potentially exacerbating Lyme disease symptoms.
  4. Attention and Concentration Challenges: Sleep-deprived individuals often grapple with maintaining focus and cognitive alertness, which can complicate the handling of daily responsibilities and informed health-related decision-making.

The Role of Jemsek Specialty Clinic in Promoting Restorative Sleep

JSC recognizes the pivotal role of sleep in the well-being of Lyme disease patients. As part of our commitment to comprehensive care, we diligently assess each patient for potential sleep hygiene issues and actively support them in achieving rejuvenating, restorative sleep. We are fully aware that neglecting these sleep challenges can significantly impact the efficacy of Lyme disease treatment.

The suggested sleep duration for those undergoing treatment is seven to eight hours per night to promote high-quality rest. Insufficient sleep can result in daytime fatigue, cognitive challenges, and musculoskeletal discomfort. Patients are advised to steer clear of substances that can disrupt their sleep, such as alcohol, appetite suppressants, and caffeine. Enhancing sleep hygiene practices stands as the primary strategy for effectively addressing insomnia.

Can adhering to a consistent bedtime routine contribute to better sleep quality?

Enhancing your sleep well-being entails establishing specific practices, such as adhering to a regular sleep timetable by retiring and rising at consistent hours daily, even on weekends. Furthermore, it proves advantageous to exclude electronic devices like televisions, computers, and smartphones from the bedroom, abstain from consuming substantial meals, caffeine, and alcohol close to bedtime, and engage in regular physical activity during the day to promote more restful nighttime sleep.

Enhancing Deep Sleep Quality in Lyme Patients

In the context of Lyme disease treatment, managing sleep disruptions is a vital element of the comprehensive wellness approach. Below, we present strategies to enhance the quality of deep sleep:

  1. Medical Treatment: Ensure that the Lyme disease is properly diagnosed and treated by a healthcare professional. Effective treatment can alleviate some of the symptoms that may be interfering with sleep.
  2. Pain Management: Lyme disease can cause joint and muscle pain. Effective pain management strategies, such as physical therapy, pain medications, or alternative therapies like acupuncture, can help reduce discomfort and improve sleep.
  3. Stress Reduction: Managing stress through relaxation techniques, such as meditation, deep breathing exercises, or yoga, can help improve sleep quality.
  4. Diet and Nutrition: Promote a well-rounded diet that fosters general well-being while potentially mitigating inflammation. Some specific foods can positively influence sleep, particularly those abundant in tryptophan, facilitating the synthesis of sleep-promoting neurotransmitters like serotonin.
  5. Exercise: Engaging in regular, moderate physical activity can enhance the quality of your sleep. However, it’s crucial to customize your exercise routines to match your unique energy levels and capabilities. Consider consulting with a healthcare provider to create a personalized exercise regimen that suits your needs and health condition.
  6. CBD Supplements: CBD oil should not be viewed as a replacement for antibiotic therapy; however, it could potentially provide relief from specific symptoms associated with post-treatment Lyme disease syndrome, including joint pain, inflammation, and sleep disturbances. It’s essential to consult with a healthcare professional to discuss the potential use of CBD oil in managing these symptoms, as individual responses may vary, and any interactions with other treatments should be carefully considered.
  7. Prescription Medications: For certain individuals, prescription medications might be required to manage sleep disturbances. It is important to discuss this option with a healthcare provider who can thoroughly evaluate the potential risks and benefits based on your specific health condition and needs.
  8. Support Groups: Participating in a Lyme disease support group can offer emotional assistance and a platform for sharing experiences and strategies for coping with symptoms and enhancing sleep quality.


In conclusion, deep sleep plays a pivotal role in preserving cognitive function and overall well-being. The impact of sleep disturbances on cognition is particularly notable for Lyme disease patients. By comprehending the link between deep sleep and cognitive health and adopting methods to improve sleep quality, individuals with Lyme disease can effectively handle their symptoms and enhance their overall quality of life. Collaborating with healthcare experts who specialize in Lyme disease is indispensable for crafting a customized strategy to address sleep problems and broader health issues. In the fight against Lyme, embracing the benefits of deep sleep can serve as a rejuvenating and empowering ally.

  1. Suni, E. (2021, December 2). Stages of sleep: What happens in a sleep cycle(N. Vyas, Ed.). Sleep Foundation.
  2. Berghoff, W. (2012). Chronic Lyme Disease and Co-infections: Differential Diagnosis. The Open Neurology Journal6(1), 158–178.×01206010158
  3. Greenberg, H. E., Ney, G., Scharf, S. M., Ravdin, L., & Hilton, E. (1995). Sleep quality in Lyme disease. Sleep18(10), 912–916.
  4. (n.d.). Anxiety and Lyme Disease. Retrieved October 27, 2023, from
  5. Lantos, P. M. (2015). Chronic Lyme Disease. Infectious Disease Clinics of North America29(2), 325–340.
  6. Lyme Disease Heightens Risk of Mental Disorders, Suicidality. (2021, August 9). Columbia University Department of Psychiatry.
  7. Columbia University Irving Medical Center. (2018, April 11). Treatment options. Lyme Disease.
  8. (2022, September 13). Sleep hygiene tips – sleep and sleep disorders. Centers for Disease Control and Prevention; Centers for Disease Control and Prevention.
  9. Lyme Disease: A Short Primer for Pain Practitioners. (2014). Practical Pain Management.
  10. Mayo Clinic. (2022, April 28). Relaxation techniques: Try these steps to reduce stress. Mayo Clinic.
  11. Sejbuk, M., Mirończuk-Chodakowska, I., & Witkowska, A. M. (2022). Sleep Quality: A Narrative Review on Nutrition, Stimulants, and Physical Activity as Important Factors. Nutrients14(9), 1912.
  12. CBD Oil for Lyme Disease: Does It Work? (2022, March 31). Healthline.
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